Ginkgo biloba Extract and Ginkgolide Antiarrhythmic Potential by Targeting hERG and ICa-L Channel
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چکیده
منابع مشابه
Ginkgo Biloba Extract: A Review
Extracts of the leaves of the Ginkgo biloba tree (ginkgo) have been used in China for medicinal purposes for hundreds of years. Research performed during the past fifteen years suggests that ginkgo may be of value in the treatment of age-related physical and mental deterioration, dementia, peripheral vascular disease, and organic impotence. Ginkgo may also reduce the severity of depression in i...
متن کاملGinkgo biloba extract: mechanisms and clinical indications.
OBJECTIVE Ginkgo biloba may have a role in treating impairments in memory, cognitive speed, activities of daily living (ADL), edema, inflammation, and free-radical toxicity associated with traumatic brain injury (TBI), Alzheimer's dementia, stroke, vasoocclusive disorders, and aging. The purpose of this review is to provide a synthesis of the mechanisms of action, clinical indications, and safe...
متن کاملGinkgo biloba leaf extract (EGb 761) enhances catalepsy induced by haloperidol and L-nitroarginine in mice.
Ginkgo biloba extract EGb 761 has been reported to have therapeutic effects which have been attributed to anti-oxidant and free radical-scavenging activities, including a direct action on nitric oxide production. L G-nitro-arginine (L-NOARG), a nitric oxide synthase inhibitor, and haloperidol, a drug that blocks dopamine receptors, are both known to induce catalepsy in rodents. Nitric oxide has...
متن کاملGinkgo biloba extract: review of CNS effects.
The marketing of Ginkgo biloba extract (GBE) products is directed to the healthy, not diseased, population primarily for the promotion and maintenance of optimal brain function, not the treatment or prevention of any specific pathological state. However, recommendations are available for the use of GBE for a myriad of diseases that generally fall into one of three categories--cerebrovascular, p...
متن کاملFibrinolytic effects of Ginkgo biloba extract.
A multitude of factors are involved in regulating the blood coagulation homeostatic processes in the body, which may ultimately lead to thromboemboli and thrombosis. The resolution of blood clots after healing is as important as clot formation at the site of a vascular lesion. This is accomplished by fibrinolytic drugs such as streptokinase (SK) and urokinase.It must be noted that administratio...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2013
ISSN: 1347-8613,1347-8648
DOI: 10.1254/jphs.13118fp